Difference between revisions of "Team:UChile OpenBio-CeBiB/Model/Results"
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Revision as of 02:33, 2 November 2017
Results
From the previous procedures, we obtained the following results:
Phase 1: The First Approach
Metabolic Pathway
We observed the production of Glucose 6-phosphate, and an increased of the intermediaries affected by FBP/SBPase. Aditionally, all the compounds reach the steady state with concentrations close to reallity, but the timeline should be reviewed. We considered this model correct for a first approach.
Genetic Pathway
The graphic shows the increase of FBP/SBPasa enzyme, which confirm the expected results. If we expand the timeline, we could observed the steady state.
Metabolic Pathway, B12 Absent
Metabolic Pathway, B12 Present
We observed that in absence of B12, the steady state is reached after than in the case of presence of the vitamin. Besides, in the first graph there is an initial accumulation of UDP-Glucose, which in the second scenario is null due to the full production of starch.
Genetic Pathway, B12 Absent
Genetic Pathway, B12 Present
We observed the same behavior of STA1 and STA6 for both cases, therefore insensitive to B12 vitamin. For GBS2 we observed the expected behavior, having a null production of protein, due to the production of antisense RNA, which is confirmed with the formation of double strand DNA.
Phase 2: Sensitivity Analysis
G6P Production from Calvin Cycle
Starch Production from Antisense
G6P Production from Calvin Cycle
Starch Production from Antisense
G6P Production from Calvin Cycle
Starch Production from Antisense
GBS2 effect on Starch Production
STA1 effect on Starch Production
STA6 effect on Starch Production
