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− | {{:Team:CPU_CHINA/ | + | {{:Team:CPU_CHINA/Templates/NavFoot}} |
+ | <html> | ||
+ | |||
+ | <head> | ||
+ | <link rel="stylesheet" href="https://2017.igem.org/Team:CPU_CHINA/css/home?action=raw&ctype=text/css"> | ||
+ | <link rel="stylesheet" href="https://2017.igem.org/Team:CPU_CHINA/css/description?action=raw&ctype=text/css"> | ||
+ | </head> | ||
+ | <style> | ||
+ | #content{ | ||
+ | width: 100%; | ||
+ | } | ||
+ | </style> | ||
+ | <body> | ||
+ | <div class="body-container"> | ||
+ | <p class="body-title" style="margin-top:80px"> | ||
+ | SynNotch CAR-Tregs V.S. Rheumatoid Arthritis | ||
+ | </p> | ||
+ | <h3>HEAD-Treg</h3> | ||
+ | <img src="./img/home-figure1.jpg" class="img-top"> | ||
+ | <video src="./other/video.mp4" controls="controls" class="video"></video> | ||
+ | <p class="body-title" style="padding-top:100px">Description</p> | ||
+ | <div class="content" style="margin-top:60px"> | ||
+ | <h4>Rheumatoid arthritis (RA) is a serious chronic, inflammatory and systemic autoimmune disease.</h4> | ||
+ | <h4>s of great essence to develop a kind of novel cell-targeted therapy for RA because there is no radical cure | ||
+ | for RA for the time being.</h4> | ||
+ | <h4>To solve the problems existing in the current treatment of RA, we design and build a brand new immunotherapy. | ||
+ | FOXP3+ regulatory T cells(Tregs), which can suppress and regulate immune reactions, are modified utilizing | ||
+ | a lentiviral vector system to express a chimeric antigen receptor(CAR) targeting inflammatory cells associated | ||
+ | with RA. </h4> | ||
+ | <h4> Meanwhile, we insert the Syn-Notch receptor to activate the functional stability pathway of Tregs in the | ||
+ | inflammatory environment, which enables them to play their role of immunosuppression in lesions more | ||
+ | efficiently and more stably.</h4> | ||
+ | <h4>These two redirections of the two different but interrelated systems on Tregs ensure this novel therapy a | ||
+ | promising anti-RA effect. </h4> | ||
+ | </div> | ||
+ | <div class="body-footer"> | ||
+ | <div class="row logo"> | ||
+ | <div class="col-md-4"> | ||
+ | <img src="./img/logo/logo1.jpg" alt=""> | ||
+ | </div> | ||
+ | <div class="col-md-4"> | ||
+ | <img src="./img/logo/logo2.png" alt=""> | ||
+ | </div> | ||
+ | <div class="col-md-4"> | ||
+ | <img src="./img/logo/logo3.jpg" alt=""> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="row logo" style="margin-top:20px"> | ||
+ | <div class="col-md-4"> | ||
+ | <img src="./img/logo/logo4.png" alt=""> | ||
+ | </div> | ||
+ | <div class="col-md-4"> | ||
+ | </div> | ||
+ | <div class="col-md-4"> | ||
+ | <img src="./img/logo/logo5.jpg" alt=""> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="row else-contact"> | ||
+ | <div class="col-md-4"> | ||
+ | <span class="foot-title">Contact Us</span> | ||
+ | <br> | ||
+ | <span class="foot-content">15605170073</span> | ||
+ | </div> | ||
+ | <div class="col-md-4"> | ||
+ | <span class="foot-title">Emial</span> | ||
+ | <br> | ||
+ | <span class="foot-content">467072280@qq.com</span> | ||
+ | </div> | ||
+ | <div class="col-md-4" style="border-right: none"> | ||
+ | <span class="foot-title">Address</span> | ||
+ | <br> | ||
+ | <span class="foot-content">南京航空航天大学</span> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | |||
+ | |||
+ | </body> | ||
+ | </html> |
Revision as of 14:21, 28 October 2017
SynNotch CAR-Tregs V.S. Rheumatoid Arthritis
HEAD-Treg
Description