Difference between revisions of "Team:Tongji China"

 
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{{Tongji_China}}
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<!-- This document, originally from getmdl.io, was modified -->
<html>
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 +
<!--
 +
  Material Design Lite
 +
  Copyright 2015 Google Inc. All rights reserved.
  
<div class="column full_size" >
+
  Licensed under the Apache License, Version 2.0 (the "License");
<img src="http://placehold.it/2000x300/d3d3d3/f2f2f2">
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  you may not use this file except in compliance with the License.
</div>
+
  You may obtain a copy of the License at
<h1>How make a homosexual fruit fly </h1>
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<p>It is reported that pharmacological manipulation of dopamine could alter their sexual behavior. Increased dopamine level may lead to male-male courtship in Drosophila. (Increased Dopamine Level Enhances Male–Male Courtship in Drosophila. Liu Tong, et al. The journal of Neuroscience). Here we use the modified Gal4-UAS system, which is a commonly used heterotopic expression system in fruit fly genetics, to realize the ubiquitous expression of Dopamine in fruit fly. </p>
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<p>According to news reports, as of May 24, 2017, there have been 22 countries in the world (Scotland in the UK) and parts of the country and overseas territories have legislated to recognize gay marriage. Same-sex human rights are increasing rapidly in the whole world. However, China hasn’t recognized same-sex marriage yet. Many homosexuals are under great pressure from their parents and the society. We want to make some change and show that homosexuality shouldn’t be unfairly demonized. </p>
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 +
      https://www.apache.org/licenses/LICENSE-2.0
  
<div class="column full_size" >
+
  Unless required by applicable law or agreed to in writing, software
<h1> Welcome to iGEM 2017! </h1>
+
  distributed under the License is distributed on an "AS IS" BASIS,
<p>Your team has been approved and you are ready to start the iGEM season! </p>
+
  WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
</div>  
+
  See the License for the specific language governing permissions and
 +
  limitations under the License
 +
-->
 +
{{Tongji_China/Header}}
 +
<html lang="en">
 +
  <head>
 +
    <meta charset="utf-8">
 +
    <meta http-equiv="X-UA-Compatible" content="IE=edge">
 +
    <meta name="description" content="2017 Tongji iGEM team wiki">
 +
    <meta name="viewport" content="width=device-width, initial-scale=1.0, minimum-scale=1.0">
 +
    <title>Tongji iGEM</title>
  
<div class="clear"></div>
+
    <script src="https://2017.igem.org/Template:Tongji_China/Javascript?action=raw&ctype=text/javascript"></script>
  
<div class="column half_size" >
+
    <!-- Page styles -->
<h5>Before you start: </h5>
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    <link rel="stylesheet" type="text/css" href="https://2017.igem.org/Template:Tongji_China/CSS?action=raw&ctype=text/css">
<p> Please read the following pages:</p>
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    <link rel="stylesheet" type="text/css" href="https://2017.igem.org/Template:Tongji_China/CSS_2?action=raw&ctype=text/css">
<ul>
+
    <link rel="stylesheet" type="text/css" href="https://2017.igem.org/Template:Tongji_China/CSS_3?action=raw&ctype=text/css">
<li>  <a href="https://2017.igem.org/Competition">Competition Hub</a> </li>
+
<li> <a href="https://2017.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li>
+
<li> <a href="https://2017.igem.org/Resources/Template_Documentation">Template documentation</a></li>
+
</ul>
+
</div>
+
  
<div class="column half_size" >
+
    <style>
<div class="highlight">
+
    #view-source {
<h5> Styling your wiki </h5>
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      position: fixed;
<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
+
      display: block;
<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
+
      right: 0;
</div>
+
      bottom: 0;
</div>
+
      margin-right: 40px;
 +
      margin-bottom: 40px;
 +
      z-index: 900;
 +
    }
  
<div class="column full_size" >
+
    a {
<h5> Wiki template information </h5>
+
      text-decoration: none;
<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2017.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
+
      color: rgba(20,20,20,1);
 +
    }
 +
    /* unvisited link */
 +
    a:link {
 +
      color: green;
 +
    }
  
</div>
+
    /* visited link */
 +
    a:visited {
 +
      color: DarkGreen;
 +
    }
  
 +
    /* mouse over link */
 +
    a:hover {
 +
      color: red;
 +
    }
  
 +
    /* selected link */
 +
    a:active {
 +
      color: blue;
 +
    }
  
 +
    .demo-card-wide.mdl-card {
 +
      margin: auto;
 +
      margin-top: 20px;
 +
      align-items: center;
 +
      width: 70%;
 +
      border-radius:6px
 +
    }
 +
    .demo-card-wide > .mdl-card__title {
 +
      color: #757575;
 +
      align-self: center;
 +
      /*height: 176px;*/
 +
    }
 +
    .demo-card-wide > .mdl-card__menu {
 +
      color: #757575;
 +
    }
  
<div class="column half_size" >
+
    .mdl-card__title-text {
<h5> Editing your wiki </h5>
+
      padding-top: 20px;
<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
+
    }
<p> <a href="https://2017.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p>
+
  
</div>
+
    .mdl-card__supporting-text {
 +
      line-height: 130%;
 +
    }
  
 +
    /*@-webkit-keyframes blinker {
 +
      from { opacity: 1.0; }
 +
      to { opacity: 0.0; }
 +
    }*/
  
<div class="column half_size" >
+
    .android-header .material-icons {
<h5>Tips</h5>
+
      color: #388E3C !important;
<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
+
      /*-webkit-animation-name: blinker;
<ul>
+
      -webkit-animation-iteration-count: 5;
<li>State your accomplishments! Tell people what you have achieved from the start. </li>
+
      -webkit-animation-timing-function: cubic-bezier(.5, 0, 1, 1);
<li>Be clear about what you are doing and how you plan to do this.</li>
+
      -webkit-animation-duration: 1.5s;*/
<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
+
    }
<li>Make sure information is easy to find; nothing should be more than 3 clicks away. </li>
+
<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
+
<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2017.igem.org/Calendar">iGEM 2017 calendar</a> </li>
+
<li>Have lots of fun! </li>
+
</ul>
+
</div>
+
  
 +
    .imagelayout{
 +
      width: 60%;
 +
    }
  
<div class="column half_size" >
+
    .chartopacity {
<h5>Inspiration</h5>
+
      opacity: 0.8;
<p> You can also view other team wikis for inspiration! Here are some examples:</p>
+
    }
<ul>
+
<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
+
<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
+
<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
+
<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
+
<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
+
<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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</ul>
+
</div>
+
  
<div class="column half_size" >
+
    .logolayout{
<h5> Uploading pictures and files </h5>
+
        width: 22% !important;
<p> You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
+
        margin: 1.5% !important;
When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)<br><br>
+
    }
  
<a href="https://2017.igem.org/Special:Upload">
+
    @font-face {
UPLOAD FILES
+
        font-family: NewCustomFont;
</a>
+
        src: url(https://static.igem.org/mediawiki/2017/8/87/2017tongji_fonts_homepage.ttf) format('truetype');
</p>
+
    }
</div>
+
  
 +
    /*DROPDOWN*/
  
 +
    .dropdown {
 +
        position: relative;
 +
        display: inline-block;
 +
        vertical-align: bottom;
 +
        width: 100px;
 +
        height: 150px;
 +
        top: 50px;
 +
        padding-left: 10px;
 +
        padding-right: 10px;
 +
    }
 +
    .dropdown a {
 +
        /*color: black;*/
 +
        /*padding: 16px;*/
 +
        text-align: center;
 +
        text-decoration: none;
 +
        /*display: block;*/
 +
        font-family: NewCustomFont;
 +
    }
 +
    /*.dropdown:hover {
 +
        background-color: rgba(255,255,255,0.66);
 +
    }*/
 +
    /*.dropdown a {
 +
      vertical-align: bottom;
 +
      z-index: 999;
 +
    }*/
 +
    /*.dropdown-back {
 +
        position: absolute;
 +
        bottom: 0px;
 +
        left: 0px;
 +
        background-color: rgba(255,255,255,0);
 +
        width: 100%;
 +
        height: 100px;
 +
    }*/
 +
    /*.dropdown:hover .dropdown-back {
 +
        background-color: rgba(255,255,255,0.66);
 +
    }*/
  
 +
    .dropdown-content {
 +
        display: none;
 +
        position: absolute;
 +
        background-color: rgba(255,255,255,0.5);
 +
        width: 140px;
 +
        /*min-width: 160px;*/
 +
        /*box-shadow: 0px 8px 16px 0px rgba(0,0,0,0.2);*/
 +
        z-index: 1;
 +
    }
 +
    .dropdown-content a {
 +
        /*color: black;*/
 +
        padding-top: 8px;
 +
        padding-bottom: 8px;
 +
        /*padding-left: 8px;*/
 +
        /*padding-right: 8px;*/
 +
        text-decoration: none;
 +
        display: block;
 +
        /*font-size: 120%;*/
 +
        font-family: NewCustomFont;
 +
    }
 +
    .dropdown:hover .dropdown-content {
 +
        display: block;
 +
    }
 +
    .dropdown-content a:hover {background-color: rgba(255,255,255,0.8)}
  
 +
    .dropdown-title {
 +
        width: 140px;
 +
    }
 +
    .dropdown-title a {
 +
      padding-top: 8px;
 +
      padding-bottom: 8px;
 +
      padding-left: 16px;
 +
      padding-right: 16px;
 +
      text-decoration: none;
 +
      display: block;
 +
      font-size: 130%;
 +
      font-family: NewCustomFont;
 +
    }
 +
    .dropdown:hover .dropdown-title {
 +
        background-color: rgba(255,255,255,0.5);
 +
    }
 +
    .dropdown-title a:hover {background-color: rgba(255,255,255,0.8)}
  
 +
    .dropdown-image {
 +
      padding-left: 20px;
 +
      padding-right: 20px;
 +
    }
  
 +
    .desktopview {
 +
      position: relative;
 +
      height: 800px;
 +
      width: auto;
 +
      background-color: #f3f3f3;
 +
      background: url('https://static.igem.org/mediawiki/2017/9/9f/2017_tongji_wiki_image_homepage_backgroud2.png') center no-repeat;
 +
      background-size: cover;
 +
    }
  
 +
    .mobileview-header {
 +
    }
 +
 +
    .mobileview-drawer {
 +
    }
 +
 +
    .mobileview-title {
 +
      padding-top: 100px
 +
    }
 +
 +
    .disappear-on-mobile {
 +
    }
 +
 +
    @media only screen and (max-device-width: 1200px) {
 +
      .demo-card-wide.mdl-card {
 +
        width: 80%;
 +
        max-width: 1500px
 +
      }
 +
  }
 +
 +
    @media only screen and (min-device-width: 900px) {
 +
      .mobileview-header {
 +
        position: absolute !important;
 +
        top: -1000px !important;
 +
      }
 +
      .mobileview-drawer {
 +
        position: absolute !important;
 +
        top: -1000px !important;
 +
      }
 +
      .mobileview-title {
 +
        position: absolute !important;
 +
        top: -1000px !important;
 +
      }
 +
    }
 +
 +
    @media only screen and (max-device-width: 900px) {
 +
      .demo-card-wide.mdl-card {
 +
        width: 90%;
 +
      }
 +
      .imagelayout {
 +
        width: 80%;
 +
      }
 +
      .logolayout{
 +
        width: 30% !important;
 +
        margin: 3% !important;
 +
      }
 +
      .desktopview {
 +
        position: absolute !important;
 +
        top: -1000px !important;
 +
        display: none !important;
 +
        background: none;
 +
      }
 +
      /*.mobileview-header {
 +
        display: flex !important;
 +
      }
 +
      .mobileview-drawer {
 +
        display: block !important;
 +
      }*/
 +
  }
 +
 +
    @media only screen and (max-device-width: 600px) {
 +
      .demo-card-wide.mdl-card {
 +
        width: 95%;
 +
      }
 +
 +
      .imagelayout {
 +
        width: 100%;
 +
      }
 +
      .logolayout{
 +
        width: 45% !important;
 +
        margin: 2% !important;
 +
      }
 +
      .disappear-on-mobile {
 +
        display:none !important;
 +
      }
 +
  }
 +
    </style>
 +
 +
    <script type="text/javascript">
 +
    // Try to remove weird iGEM side menu and resize the remaining things
 +
    function closeMenuDiv(){
 +
      document.getElementById("sideMenu").style.display = "none";
 +
      bars_box_active = false;
 +
      document.getElementById('content').setAttribute("style","display:block;width:100%");
 +
      document.getElementById('content').style.width='100%';
 +
    }
 +
    window.setTimeout(closeMenuDiv,0);
 +
    window.setTimeout(closeMenuDiv,10);
 +
    window.setTimeout(closeMenuDiv,20);
 +
    window.setTimeout(closeMenuDiv,50);
 +
    window.setTimeout(closeMenuDiv,100);
 +
    window.setTimeout(closeMenuDiv,200);
 +
    window.setTimeout(closeMenuDiv,500);
 +
    window.setTimeout(closeMenuDiv,1000);
 +
    window.setTimeout(closeMenuDiv,2000);
 +
    window.setTimeout(closeMenuDiv,5000);
 +
    window.setTimeout(closeMenuDiv,10000);
 +
    window.setTimeout(closeMenuDiv,20000);
 +
 +
    function playIntroVideo(){
 +
      document.getElementById("playbutton").style.display = "none";
 +
      document.getElementById('IntroVideo').play();
 +
    }
 +
    </script>
 +
 +
  </head>
 +
  <body>
 +
    <div class="mdl-layout mdl-js-layout mdl-layout--fixed-header" class="main view" style="background:#f9f9f9">
 +
      <a name="top"></a>
 +
 +
      <!-- MOBILE VIEW -->
 +
      <!-- Header -->
 +
      <div class="android-header mdl-layout__header mdl-layout__header--waterfall mobileview-header">
 +
        <div class="mdl-layout__header-row">
 +
          <span class="android-title mdl-layout-title">
 +
            <div class="logo-font">Tongji iGEM</div>
 +
          </span>
 +
          <!-- Add spacer, to align navigation to the right in desktop -->
 +
          <div class="android-header-spacer mdl-layout-spacer"></div>
 +
          <!-- Navigation -->
 +
          <div class="android-navigation-container">
 +
            <nav class="android-navigation mdl-navigation">
 +
              <!-- Links in the top right -->
 +
              <a class="mdl-navigation__link mdl-typography--text-uppercase" href="https://2017.igem.org/Team:Tongji_China">Home</a>
 +
              <a class="mdl-navigation__link mdl-typography--text-uppercase" href="https://2017.igem.org/Team:Tongji_China/Description">Project</a>
 +
              <a class="mdl-navigation__link mdl-typography--text-uppercase" href="https://2017.igem.org/Team:Tongji_China/Team">Team</a>
 +
              <a class="mdl-navigation__link mdl-typography--text-uppercase" href="https://2017.igem.org/Team:Tongji_China/Results">Results</a>
 +
            </nav>
 +
          </div>
 +
          <span class="android-mobile-title mdl-layout-title">
 +
            <div class="logo-font">Tongji iGEM</div>
 +
          </span>
 +
        </div>
 +
      </div>
 +
      <!-- Drawer -->
 +
      <div class="android-drawer mdl-layout__drawer mobileview-drawer">
 +
        <nav class="mdl-navigation">
 +
          <!-- <span class="mdl-navigation__link" href="">Title</span> -->
 +
          <a class="mdl-navigation__link" style="color: #388E3C" href="https://2017.igem.org/Team:Tongji_China">HOME</a>
 +
          <div class="android-drawer-separator"></div>
 +
 +
          <a class="mdl-navigation__link" style="color: #388E3C">PROJECT</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Description">Description</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Design">Design</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Results">Results</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Demonstrate">Demonstrate</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Record">Record</a>
 +
          <!-- <div class="android-drawer-separator"></div> -->
 +
 +
          <a class="mdl-navigation__link" style="color: #388E3C">LAB</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Parts">Parts</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Experiments">Tests</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/InterLab">InterLab</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Process">Process</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Protocol">Protocol</a>
 +
          <!-- <div class="android-drawer-separator"></div> -->
 +
 +
          <a class="mdl-navigation__link" style="color: #388E3C" href="https://2017.igem.org/Team:Tongji_China/Model">MODEL</a>
 +
          <!-- <div class="android-drawer-separator"></div> -->
 +
 +
          <a class="mdl-navigation__link" style="color: #388E3C" href="https://2017.igem.org/Team:Tongji_China/Human_Practices">HP</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/HP/Silver">Silver</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/HP/Gold_Integrated">Gold</a>
 +
          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Engagement">Engagement</a>
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          <a class="mdl-navigation__link" style="color: #388E3C" href="https://2017.igem.org/Team:Tongji_China/Safety">SAFETY</a>
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          <!-- <div class="android-drawer-separator"></div> -->
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          <a class="mdl-navigation__link" style="color: #388E3C">AWARDS</a>
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          <a class="mdl-navigation__link" style="margin-left:8px;" href="https://2017.igem.org/Team:Tongji_China/Judging_Form">Judging Form</a>
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          <a class="mdl-navigation__link" style="color: #388E3C">TEAM</a>
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      <!-- HERE STARTS THE PAGE -->
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        <a name="top"></a>
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        <!-- Title and Subtitle -->
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        <div class="mdl-typography--text-center mobileview-title" style="height:700px; background:url('https://static.igem.org/mediawiki/2017/9/9f/2017_tongji_wiki_image_homepage_backgroud2.png') center no-repeat; background-size:cover;">
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          <div class="logo-font android-slogan" style="color:#388E3C;">Ignis Fly</div>
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            Welcome to our wiki!<br>
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        <!-- DESKTOP VIEW -->
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            <img style="margin-top:250px; width:600px; opacity:0.8" src="https://static.igem.org/mediawiki/2017/3/3b/2017_tongji_wiki_homepage_title-NEW.png" alt="Ignis Fly">
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                </a>
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                    Model
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                  </a>
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                  </a>
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                  </a>
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                </a>
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                    Awards
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                  </a>
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                    Judging Form
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                  </a>
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                    Model
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                  </a>
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                  <!-- <div class="dropdown-title">HP</div> -->
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                </a>
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                    HP
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                  </a>
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                  <a href="https://2017.igem.org/Team:Tongji_China/HP/Silver" style="font-family: NewCustomFont;">
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                    HP Silver
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                  </a>
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                  <a href="https://2017.igem.org/Team:Tongji_China/HP/Gold_Integrated" style="font-family: NewCustomFont;">
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                    HP Gold
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                  </a>
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                    Engagement
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                  </a>
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                </a>
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                  </a>
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                  </a>
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                  </a>
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                  </a>
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                    Design
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                  </a>
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                    Results
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                  </a>
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                </a>
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                  </a>
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                  </a>
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                    Collaborations
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                  </a>
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                    Attributions
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                  </a>
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                  </a>
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                  </a>
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                  </a>
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 +
 +
        <!-- Video -->
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          <video width="100%" poster="https://static.igem.org/mediawiki/2017/a/aa/2017tongji_images_home_introduction_poster.jpg" id="IntroVideo" controls>
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            <source src="https://static.igem.org/mediawiki/2017/5/52/2017tongji_video_home_introduction.mp4" type="video/mp4">
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              Your browser does not support the video tag.
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        </div>
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        <!-- Description -->
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        <div class="demo-card-wide mdl-card mdl-shadow--2dp">
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          <div class="mdl-card__title" style="text-align:center">
 +
            <h4 class="mdl-card__title-text" style="font-size: 250%; color:#5a5a5a">The Project</h4>
 +
          </div>
 +
          <div class="mdl-card__supporting-text" style="font-size: 115%">
 +
            There are many people who die of diseases that are spread by mosquitoes such as malaria, dengue fever and Zika. According to a WHO’s report, there are 429,000 deaths from malaria occurred in 2015. With our project we hope to help them.<br><br>
 +
 +
            We had the idea for our project after we found an article reporting that pharmacological manipulation of dopamine levels could alter the sexual behaviour of fruits flies. Since mosquitoes and fruit flies both belong to Diptera, the system that was used in flies could also be used in mosquitos. We realised that this could be a way to control the mosquito population, giving use greater control over disease carrying mosquitos without wiping them out entirely.
 +
            For this reason we used the specificity promoter pleP that is only activated in dopaminergic neuron and the Gal80ts protein that is only activated in low temperature condition, and the UAS-GAL4 system to alter the sexual behaviour of fruits flies and control their population.<br><br>
 +
 +
            We are proud to say that our system has given promising results in our experiments and model. This is not the end though, we can continue to optimise our system. For example, we could put the constructs in a single chromosome. We could also extend our system to make it work at different temperatures (and thus environments). This way we will join Oxitec Mosquito and Wolbachia in the fight against disease carrying mosquitoes!
 +
          </div>
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          One Logo
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          One Logo
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            <img src="LINK TO LOGO EDITME" alt="LOGO NAME EDITME" style="width:100%">
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          </div>
 +
        </div> -->
 +
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 +
          <img class="imagelayout" style="width: 25%" src="https://static.igem.org/mediawiki/2017/8/82/2017_tongji_wiki_image_homepage_logo_of_tongji.png" alt="Ignis Fly">
 +
          <br>
 +
          <img class="imagelayout" src="https://static.igem.org/mediawiki/2017/b/b6/2017_tongji_wiki_image_homepage_logo.png">
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        </div>
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        <!-- Go back Home -->
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                Contact us:<br>
 +
                Tel: +86-21-65982200<br>
 +
                Email: <a style="padding:0" href="mailto:tju_igem_2017@163.com?Subject=iGEM" target="_top">tju_igem_2017@163.com</a><br>
 +
                Twitter: <a style="padding:0" href="https://twitter.com/iGEM_Tongji_CN">@iGEM_Tongji_CN</a>
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              <div class="mdl-typography--display-2 mdl-typography--font-thin">Ignis Fly</div>
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 +
                Tongji_China iGEM 2017 Team<br>
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Latest revision as of 02:54, 2 November 2017


Tongji iGEM
Tongji iGEM
Tongji iGEM
Ignis Fly
Welcome to our wiki!

The Project

There are many people who die of diseases that are spread by mosquitoes such as malaria, dengue fever and Zika. According to a WHO’s report, there are 429,000 deaths from malaria occurred in 2015. With our project we hope to help them.

We had the idea for our project after we found an article reporting that pharmacological manipulation of dopamine levels could alter the sexual behaviour of fruits flies. Since mosquitoes and fruit flies both belong to Diptera, the system that was used in flies could also be used in mosquitos. We realised that this could be a way to control the mosquito population, giving use greater control over disease carrying mosquitos without wiping them out entirely. For this reason we used the specificity promoter pleP that is only activated in dopaminergic neuron and the Gal80ts protein that is only activated in low temperature condition, and the UAS-GAL4 system to alter the sexual behaviour of fruits flies and control their population.

We are proud to say that our system has given promising results in our experiments and model. This is not the end though, we can continue to optimise our system. For example, we could put the constructs in a single chromosome. We could also extend our system to make it work at different temperatures (and thus environments). This way we will join Oxitec Mosquito and Wolbachia in the fight against disease carrying mosquitoes!
Ignis Fly
Contact us:
Tel: +86-21-65982200
Email: tju_igem_2017@163.com
Twitter: @iGEM_Tongji_CN
Ignis Fly

Tongji_China iGEM 2017 Team
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