Team:US AFRL CarrollHS/HP/Gold Integrated
This part is a growth inhibition device makes a cell release BMP2 that can slow or stop the growth of bacteria. In the future, this part can be modified to keep the cell population of our E. coli controlled in the colon of humans or in water. It would allow the cells to not grow and overtake the cells that are already living in the ecosystem. This part is already modified for cells in the colon and could be a great addition to our E. coli. This part uses the double cellulose binding domain (dCBD) that is part of the packaging for our E. coli. This dCBD linker creates a site within the dCBD that binds the cellulose to a metal. This can be useful for our project if we combine it with our dCDB, because it could recognize the presence of a metal with the potential to harm humans when the E. coli cells are in the digestive system or water sample. With this additional part, the cellulose would bind to the metal and trap it and can then be tested for different metals.
Integrated Human Practices
iGEM Registry Part: Bba_k733012
iGEM Registry Part: Part:BBa_K1321110
